Secondary Metabolites of the Rice Blast Fungus Pyricularia oryzae: Biosynthesis and Biological Function

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The Potential of Streptomyces as Biocontrol Agents against the Rice Blast Fungus, Magnaporthe oryzae (Pyricularia oryzae)

Rice is a staple food source for more than three billion people worldwide. However, rice is vulnerable to diseases, the most destructive among them being rice blast, which is caused by the fungus Magnaporthe oryzae (anamorph Pyricularia oryzae). This fungus attacks rice plants at all stages of development, causing annual losses of approximately 10-30% in various rice producing regions. Syntheti...

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Growth in rice cells requires de novo purine biosynthesis by the blast fungus Magnaporthe oryzae

Increasing incidences of human disease, crop destruction and ecosystem perturbations are attributable to fungi and threaten socioeconomic progress and food security on a global scale. The blast fungus Magnaporthe oryzae is the most devastating pathogen of cultivated rice, but its metabolic requirements in the host are unclear. Here we report that a purine-requiring mutant of M. oryzae could dev...

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Methionine Biosynthesis is Essential for Infection in the Rice Blast Fungus Magnaporthe oryzae

Methionine is a sulfur amino acid standing at the crossroads of several biosynthetic pathways. In fungi, the last step of methionine biosynthesis is catalyzed by a cobalamine-independent methionine synthase (Met6, EC 2.1.1.14). In the present work, we studied the role of Met6 in the infection process of the rice blast fungus, Magnaporthe oryzae. To this end MET6 null mutants were obtained by ta...

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Pathogenic Variation and Molecular Characterization of Pyricularia oryzae, Causal Agent of Rice Blast Disease in Tanzania

Rice blast disease, caused by the fungus Pyricularia oryzae, is one of the most devastating diseases of rice. Understanding pathogenic variation and molecular characterization of P. oryzae is one of the most efficient ways to manage the disease. Studies on identification, characterization and pathogenic variation of P. oryzae were conducted in the laboratory and screen-house at Sokoine Universi...

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2020

ISSN: 1422-0067

DOI: 10.3390/ijms21228698